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Products

A Single-molecule Protein Interaction Detection(SPID) platform
for exploring Protein Dynamics

Quantitative, highly-reproducible bioinformation obtained from PROTEINA single-molecule co-immunoprecipitation technology permits the direct integration
of measured data sets obtained at multiple locations and timepoints, facilitating the discovery of novel biomarkers and therapeutic treatments

  • Products
  • Assay

PROTEINA PathFinder BCL2 assay

Receive insightful information to maximize the benefits of BCL2 inhibitor therapy for best possible outcome and enhance survival.

Biomarker

BCL2-BIM PBA, BCL2 Lv, BCL2-BAX CPX

BCLXL-BIM PBA, BCLXL-BAK CPX

MCL1-BIM PBA, MCL1-BAK CPX, MCL1 Lv

* PBA = Probe Binding Assay

* CPX = Complex

* Lv = Expression level

※ Click on the image to see detailed information.

Pi-Chip

Suppressing non-specific binding provides true-positive signal at high confidence & sensitivity

Assay Workflow

Extraction & Detection01

PROTEINA PathFinder BCL2 assay

Targeted protein complexes are isolated from the sample and blended with PROTEINA
specialized reagents. The mixture is then placed in the wells of the Pi-Chip, where
fluorescent-signaling antibodies will attach to proteins of interest.

Quantification02

Pi-View

PROTEINA Pi-View detects each protein complex as a point
in a displayed image

Analysis03

Pi-Insight

PROTEINA Pi-Insight analysis software produces a summarized
user-friendly report detailing actionable data.

PROTEINA PathFinder BCL2 assay is Research Use Only.

PROTEINA PathFinder BCL2 assay is compatible with PROTEINA Pi-View

Brochure

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